Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations

von Wyl, Viktor; Yerly Ferrillo, Sabine; Böni, Jürg; Shah, Cyril; Cellerai, Cristina; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Cavassini, Matthias; Furrer, Hansjakob; Hirschel, Bernard; Vernazza, Pietro L; Ledergerber, Bruno; Günthard, Huldrych F

doi:10.1093/cid/cir728

Scientific article

Open access

English

Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations

Contributorsvon Wyl, Viktor; Yerly Ferrillo, Sabine; Böni, Jürg; Shah, Cyril; Cellerai, Cristina; Klimkait, Thomas; Battegay, Manuel; Bernasconi, Enos; Cavassini, Matthias; Furrer, Hansjakob; Hirschel, Bernard; Vernazza, Pietro L; Ledergerber, Bruno; Günthard, Huldrych F

Published inClinical infectious diseases, vol. 54, no. 1, p. 131-140

Publication date2012

Abstract

Estimates of drug resistance incidence to modern first-line combination antiretroviral therapies against human immunodeficiency virus (HIV) type 1 are complicated by limited availability of genotypic drug resistance tests (GRTs) and uncertain timing of resistance emergence.

Keywords

Adult
Anti-HIV Agents/administration & dosage/pharmacology
Drug Resistance, Viral
Female
Genotype
HIV Infections/drug therapy/virology
HIV-1/classification/drug effects/genetics/isolation & purification
Humans
Incidence
Male
Middle Aged
Treatment Outcome
Viral Load

Affiliation

Faculté de médecine / Section de médecine clinique / Département de médecine

Research group

Groupe Laurent Kaiser (virologie clinique) (668)

Citation (ISO format)

VON WYL, Viktor et al. Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations. In: Clinical infectious diseases, 2012, vol. 54, n° 1, p. 131–140. doi: 10.1093/cid/cir728

Article (Published version)

Identifiers

PID : unige:74520
DOI : 10.1093/cid/cir728
PMID : 22057700

ISSN of the journal1058-4838

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Incidence of HIV-1 drug resistance among antiretroviral treatment-naive individuals starting modern therapy combinations

Estimates of drug resistance incidence to modern first-line combination antiretroviral therapies against human immunodeficiency virus (HIV) type 1 are complicated by limited availability of genotypic drug resistance tests (GRTs) and uncertain timing of resistance emergence.

Technical informations