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Use of Treponema pallidum PCR in testing of ulcers for diagnosis of primary syphilis

ContributorsGayet-Ageron, Angèleorcid; Sednaoui, Patrice; Lautenschlager, Stephan; Ferry, Tristan; Toutous Trellu, Laurence Marieorcid; Cavassini, Matthias; Yassir, Fatima; Martinez De Tejada Weber, Begona; Emonet, Stéphaneorcid; Combescure, Christopheorcid; Schrenzel, Jacques; Perneger, Thomas
Published inEmerging infectious diseases, vol. 21, no. 1, p. 127-129
Publication date2015
Abstract

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.

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GAYET-AGERON, Angèle et al. Use of Treponema pallidum PCR in testing of ulcers for diagnosis of primary syphilis. In: Emerging infectious diseases, 2015, vol. 21, n° 1, p. 127–129. doi: 10.3201/eid2101.140790
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Journal ISSN1080-6040
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Creation16/06/2015 13:13:00
First validation16/06/2015 13:13:00
Update13/10/2025 21:20:30
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