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Scientific article
English

Performance of the 47-kilodalton membrane protein versus DNA polymerase i genes for detection of Treponema pallidum by PCR in ulcers

Published inJournal of clinical microbiology, vol. 53, no. 3, p. 976-980
Publication date2015
Abstract

Treponema pallidum PCR (Tp-PCR) is a direct diagnostic method for primary and secondary syphilis, but there is no recommendation regarding the best choice of target gene. In this study, we sequentially tested 272 specimens from patients with sexually transmitted ulcers using Tp-PCR targeting the tpp47 and then polA genes. The two methods showed similar accuracies and an almost-perfect agreement.

Citation (ISO format)
GAYET-AGERON, Angèle et al. Performance of the 47-kilodalton membrane protein versus DNA polymerase i genes for detection of Treponema pallidum by PCR in ulcers. In: Journal of clinical microbiology, 2015, vol. 53, n° 3, p. 976–980. doi: 10.1128/JCM.03444-14
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ISSN of the journal0095-1137
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Technical informations

Creation06/15/2015 4:12:00 PM
First validation06/15/2015 4:12:00 PM
Update time03/14/2023 11:28:16 PM
Status update03/14/2023 11:28:15 PM
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