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Lung disease and brain development

Amato, Maurizio
Published in Biology of the Neonate. 2006, vol. 89, no. 4, p. 284-97
Abstract With the technical progress made in fetal and neonatal intensive care, perinatal mortality has decreased by 25% over the last decade and has expanded the surviving premature population. Prematurity drastically changes the environment of the developing organism. Striking evidence from a number of disciplines has focused attention on the interplay between the developing organism and the circumstances in which it finds itself. The environmental event during a sensitive period in development, induces injury and/or biological adaptations that lead to altered differentiation of tissues. The organism can express specific adaptive responses to its environment which include short-term changes in physiology as well as long-term adjustments. This review addresses these short-term as well as longer-term changes occurring in lung and brain tissue and illustrates how these changes can be studied using advanced imaging techniques such as magnetic resonance imaging
Keywords AnimalsBrain/growth & development/pathology/physiology/radiographyGlucocorticoids/metabolismHumansInflammation/metabolismLung Diseases/epidemiology/metabolism/pathologyNeuronal PlasticityOxidative Stress
PMID: 16770068
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Research group L'imagerie cérébrale (184)
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HÜPPI, Petra Susan, SIZONENKO, Stéphane, AMATO, Maurizio. Lung disease and brain development. In: Biology of the Neonate, 2006, vol. 89, n° 4, p. 284-97. doi: 10.1159/000092865 https://archive-ouverte.unige.ch/unige:73126

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Deposited on : 2015-06-09

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