The role of endothelin-1 in hyperoxia-induced lung injury in mice

Habre, Walid; Petak, Ferenc; Ruchonnet, Isabelle; Donati, Yves Richard; Tolsa, Jean-Francois; Lele, Eniko; Albu, Gergely; Beghetti, Maurice; Barazzone, Constance

doi:10.1186/1465-9921-7-45

Scientific article

English

The role of endothelin-1 in hyperoxia-induced lung injury in mice

ContributorsHabre, Walid; Petak, Ferenc; Ruchonnet, Isabelle

; Donati, Yves Richard; Tolsa, Jean-Francois; Lele, Eniko; Albu, Gergely; Beghetti, Maurice; Barazzone, Constance

Published inRespiratory research, vol. 7, 45

Publication date2006

Abstract

As prolonged hyperoxia induces extensive lung tissue damage, we set out to investigate the involvement of endothelin-1 (ET-1) receptors in these adverse changes.

Keywords

Airway Resistance/drug effects
Animals
Endothelin-1/blood/pharmacology
Female
Hyperoxia/blood/metabolism/physiopathology
Lung/drug effects/metabolism/physiopathology
Lung Diseases/blood/metabolism/physiopathology
Mice
Mice, Inbred C57BL
Models, Biological
Pyridines/pharmacology
Receptors, Endothelin/drug effects/metabolism
Tetrazoles/pharmacology
Time Factors
Vasodilator Agents/pharmacology

Affiliation entities

Research groups

Citation (ISO format)

HABRE, Walid et al. The role of endothelin-1 in hyperoxia-induced lung injury in mice. In: Respiratory research, 2006, vol. 7, p. 45. doi: 10.1186/1465-9921-7-45

Article (Published version)

Identifiers

PID : unige:73121
DOI : 10.1186/1465-9921-7-45
PMID : 16566828

Journal ISSN1465-9921

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The role of endothelin-1 in hyperoxia-induced lung injury in mice

As prolonged hyperoxia induces extensive lung tissue damage, we set out to investigate the involvement of endothelin-1 (ET-1) receptors in these adverse changes.

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