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Neuro-otological manifestations in different stages of HIV infection

Hausler, R.
Vibert, D.
Koralnik, I. J.
Published in Acta oto-laryngologica. Supplementum. 1991, vol. 111, no. s481, p. 515-521
Abstract A systematic investigation of the incidence and type of peripheral and central auditory and vestibular disorders occurring in different stages of HIV infection was performed: 43 HIV-seropositive patients (14 were symptomatic with manifestation of AIDS or related complex and 29 were clinically asymptomatic) were compared with a matched control group of 33 HIV-seronegative homosexual volunteers. Among the symptomatic patients 8 (57%) out of 14 and among the asymptomatic HIV-positive patients, 13 (45%) out of 29 had abnormal results in various audiological, vestibular and electrophysiological tests. Only minor anomalies were found in 4 (12%) of the 33 seronegative homosexuals. Our results indicate a high incidence of neuro-otological disorders among patients suffering from AIDS. The numerous electrophysiological abnormalities found in asymptomatic HIV-seropositive persons suggest furthermore an early subclinical involvement of the auditory and vestibular systems.
Keywords AIDS-Related Complex/complicationsAcquired Immunodeficiency Syndrome/complicationsAdolescentAdultAudiometryElectronystagmographyEvoked Potentials, Auditory, Brain Stem/physiologyFemaleHIV Infections/ complications/immunologyHearing Disorders/ etiology/physiopathologyHumansMaleMiddle AgedVestibular Diseases/ etiology/physiopathologyVestibular Function Tests
PMID: 1927460
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HAUSLER, R. et al. Neuro-otological manifestations in different stages of HIV infection. In: Acta oto-laryngologica. Supplementum, 1991, vol. 111, n° s481, p. 515-521. doi: 10.3109/00016489109131461 https://archive-ouverte.unige.ch/unige:7312

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Deposited on : 2010-06-21

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