Scientific article
Case report

Fatal myocardial aspergillosis in an immunosuppressed child

Published inJournal of pediatric hematology/oncology, vol. 23, no. 7, p. 456-459
Publication date2001

A girl with resistant acute myeloid leukemia (AML) had a stem cell transplantation. Preceding transplantation, she had recurrent pneumonitis. No causative agent was identified. Despite several antibiotics including high-dose liposomal amphotericin-B, pulmonary infection progressed. Aspergillosis, always considered, could not be documented. She died from cardiac arrest on the second day after transplantation, with no forewarning of previous heart disease. Pericardial and myocardial aspergillosis was an autopsy finding. Pericardial and myocardial aspergillosis, rare manifestations of systemic aspergillosis, should be considered in any immunocompromised patient with long-lasting pulmonary infection, even in the absence of specific cardiac findings.

  • Amphotericin B/therapeutic use
  • Antifungal Agents/therapeutic use
  • Aspergillosis/diagnosis/drug therapy/microbiology
  • Aspergillus/isolation & purification
  • Child
  • Fatal Outcome
  • Female
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Immunocompromised Host
  • Leukemia, Myeloid, Acute/complications/drug therapy
  • Lung Diseases, Fungal/drug therapy/microbiology
  • Myocarditis/diagnosis/drug therapy/microbiology
  • Pericarditis/diagnosis/drug therapy/microbiology
Citation (ISO format)
OZSAHIN, Ayse Hulya et al. Fatal myocardial aspergillosis in an immunosuppressed child. In: Journal of pediatric hematology/oncology, 2001, vol. 23, n° 7, p. 456–459. doi: 10.1097/00043426-200110000-00013
Main files (1)
Article (Published version)
ISSN of the journal1077-4114

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