UNIGE document Scientific Article - Case report
previous document  unige:72632  next document
add to browser collection

Fatal myocardial aspergillosis in an immunosuppressed child

Authors show hidden authors show all authors [1 - 11]
Published in Journal of pediatric hematology/oncology. 2001, vol. 23, no. 7, p. 456-9
Abstract A girl with resistant acute myeloid leukemia (AML) had a stem cell transplantation. Preceding transplantation, she had recurrent pneumonitis. No causative agent was identified. Despite several antibiotics including high-dose liposomal amphotericin-B, pulmonary infection progressed. Aspergillosis, always considered, could not be documented. She died from cardiac arrest on the second day after transplantation, with no forewarning of previous heart disease. Pericardial and myocardial aspergillosis was an autopsy finding. Pericardial and myocardial aspergillosis, rare manifestations of systemic aspergillosis, should be considered in any immunocompromised patient with long-lasting pulmonary infection, even in the absence of specific cardiac findings.
Keywords Amphotericin B/therapeutic useAntifungal Agents/therapeutic useAspergillosis/diagnosis/drug therapy/microbiologyAspergillus/isolation & purificationChildFatal OutcomeFemaleHematopoietic Stem Cell TransplantationHumansImmunocompromised HostLeukemia, Myeloid, Acute/complications/drug therapyLung Diseases, Fungal/drug therapy/microbiologyMyocarditis/diagnosis/drug therapy/microbiologyPericarditis/diagnosis/drug therapy/microbiology
PMID: 11878582
Full text
Article (Published version) (345 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
Radiologie neuro-diagnostique et neuro-interventionnelle en pédiatrie (842)
(ISO format)
OZSAHIN, Ayse Hulya et al. Fatal myocardial aspergillosis in an immunosuppressed child. In: Journal of pediatric hematology/oncology, 2001, vol. 23, n° 7, p. 456-9. doi: 10.1097/00043426-200110000-00013 https://archive-ouverte.unige.ch/unige:72632

445 hits

0 download


Deposited on : 2015-05-18

Export document
Format :
Citation style :