Capnocytophaga canimorsus sepsis complicated by myocardial infarction in two patients with normal coronary arteries

Ehrbar, H. U.; Gubler, J.; Harbarth, Stéphan Juergen; Hirschel, Bernard

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Title		Capnocytophaga canimorsus sepsis complicated by myocardial infarction in two patients with normal coronary arteries
Authors		Ehrbar, H. U. Gubler, J. Harbarth, Stéphan Juergen Hirschel, Bernard
Published in		Clinical Infectious Diseases. 1996, vol. 23, no. 2, p. 335-336
Abstract		We describe two patients who had acute myocardial infarctions during episodes of Capnocytophaga canimorsus sepsis. C. canimorsus is associated with severe infection in patients who are immunocompromised; one of these patients had undergone splenectomy for Hodgkin's disease 11 years earlier, and the other consumed significant amounts of alcohol regularly. Both patients owned dogs that had licked them or produced minor skin wounds shortly before they became ill. Coronary angiographic findings were normal for both patients. The association of acute myocardial infarction and sepsis with a specific pathogen is unique. This finding suggests that endothelial damage and coronary thrombosis due to C. canimorsus sepsis is a possible mechanism of acute myocardial necrosis.
Keywords		Animals — Arteries — Capnocytophaga/ isolation & purification — Coronary Vessels/ physiology — Dogs — Gram-Negative Bacterial — Infections/complications/ microbiology/physiopathology/therapy — Humans — Male — Middle Aged — Myocardial Infarction/complications/ microbiology — Sepsis/complications/ microbiology/physiopathology/therapy
Identifiers		DOI: 10.1093/clinids/23.2.335 PMID: 8842273
Full text		Article - Limited access to UNIGE Other version: http://www.jstor.org/stable/pdfplus/4459611.pdf
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Research group		Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
Citation (ISO format)		EHRBAR, H. U. et al. Capnocytophaga canimorsus sepsis complicated by myocardial infarction in two patients with normal coronary arteries. In: Clinical Infectious Diseases, 1996, vol. 23, n° 2, p. 335-336. https://archive-ouverte.unige.ch/unige:7189