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Epidemiology of methicillin-resistant Staphylococcus aureus: results of a nation-wide survey in Switzerland

Blanc, Dominique
Ruef, Christian
Widmer, A. F.
Muhlemann, Kathrin
Petignat, Christiane
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Published in Swiss Medical Weekly. 2002, vol. 132, no. 17-18, p. 223-229
Abstract OBJECTIVE: To assess the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in Switzerland. MATERIAL AND METHODS: One-year national survey of all MRSA cases detected in a large sample of Swiss healthcare institutions (HCI). Analysis of epidemiological and molecular typing data (PFGE) of MRSA strains. RESULTS: During 1997, 385 cases of MRSA were recorded in the 5 university hospitals, in 33 acute care community hospitals, and 14 rehabilitation or long-term care institutions. Half of the cases were found at the University of Geneva Hospitals where MRSA was already known to be endemic (41.1 cases/10,000 admissions). The remaining cases (200) were distributed throughout Switzerland. The highest rates (>100 cases/10,000 admissions) were reported from non-acute care institutions. Rates ranged from 3.3 to 41.1 cases/10,000 admissions for university hospitals (mean 15.5); 0.67 to 90.4 for community hospitals (mean 4.8), and 28.2 to 315 for non-acute care institutions reporting MRSA (mean 85.7). Forty percent of MRSA patients were infected, while 60% were only colonised. The leading infection sites were skin and soft tissue (21%), surgical site (15%), and the urinary tract (26%). Whereas in Eastern Swiss HCI most MRSA cases occurred in acute care hospitals (n = 47, 98%), rehabilitation and long-term care institutions accounted for an important number of the identified cases (n = 107, 38%) in Western Switzerland. CONCLUSION: Low rates of MRSA were still observed in Swiss HCI, despite one outlying acute care centre with endemic MRSA and some nonacute care institutions with epidemic MRSA. Rehabilitation and long-term care institutions contributed to a substantial proportion of cases in Western Switzerland and may constitute a significant reservoir. Overall, a national approach to surveillance and control of MRSA is mandatory in order to preserve a still favourable situation, and to decrease the risk of epidemic MRSA dissemination.
Keywords AdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHealth SurveysHumansInfantMaleMethicillin ResistanceMiddle AgedStaphylococcal Infections/diagnosis/ epidemiology/prevention & controlStaphylococcus aureus/ isolation & purificationSwitzerland/epidemiology
PMID: 12087488
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Research groups Epidémiologie et contrôle de la résistance aux antibiotiques (866)
Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière (330)
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BLANC, Dominique et al. Epidemiology of methicillin-resistant Staphylococcus aureus: results of a nation-wide survey in Switzerland. In: Swiss Medical Weekly, 2002, vol. 132, n° 17-18, p. 223-229. https://archive-ouverte.unige.ch/unige:7113

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Deposited on : 2010-06-21

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