Epidemiology of methicillin-resistant Staphylococcus aureus: results of a nation-wide survey in Switzerland

Article Article scientifique Article Epidemiology of methicillin-resistant Staphylococcus aureus: results of a nation-wide survey in Switzerland eng 2002 author Blanc Dominique author Pittet Didier 117792 author Ruef Christian author Widmer A. F. author Muhlemann Kathrin author Petignat Christiane author Harbarth Stéphan Juergen 0000-0002-3551-1025 93885 author Auckenthaler Raymond 23033 author Bille Jacques author Frei Reno author Zbinden Reinhard author Peduzzi Raffaele author Gaia Valeria author Khamis Huma Fozia 95509 author Bernasconi Enos 663410 author Francioli Patrick 223-229 12087488 0036-7672 http://www.smw.ch/dfe/set_archiv.asp?target=2002/17/smw-09934 OBJECTIVE: To assess the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in Switzerland. MATERIAL AND METHODS: One-year national survey of all MRSA cases detected in a large sample of Swiss healthcare institutions (HCI). Analysis of epidemiological and molecular typing data (PFGE) of MRSA strains. RESULTS: During 1997, 385 cases of MRSA were recorded in the 5 university hospitals, in 33 acute care community hospitals, and 14 rehabilitation or long-term care institutions. Half of the cases were found at the University of Geneva Hospitals where MRSA was already known to be endemic (41.1 cases/10,000 admissions). The remaining cases (200) were distributed throughout Switzerland. The highest rates (>100 cases/10,000 admissions) were reported from non-acute care institutions. Rates ranged from 3.3 to 41.1 cases/10,000 admissions for university hospitals (mean 15.5); 0.67 to 90.4 for community hospitals (mean 4.8), and 28.2 to 315 for non-acute care institutions reporting MRSA (mean 85.7). Forty percent of MRSA patients were infected, while 60% were only colonised. The leading infection sites were skin and soft tissue (21%), surgical site (15%), and the urinary tract (26%). Whereas in Eastern Swiss HCI most MRSA cases occurred in acute care hospitals (n = 47, 98%), rehabilitation and long-term care institutions accounted for an important number of the identified cases (n = 107, 38%) in Western Switzerland. CONCLUSION: Low rates of MRSA were still observed in Swiss HCI, despite one outlying acute care centre with endemic MRSA and some nonacute care institutions with epidemic MRSA. Rehabilitation and long-term care institutions contributed to a substantial proportion of cases in Western Switzerland and may constitute a significant reservoir. Overall, a national approach to surveillance and control of MRSA is mandatory in order to preserve a still favourable situation, and to decrease the risk of epidemic MRSA dissemination. Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Female Health Surveys Humans Infant Male Methicillin Resistance Middle Aged Staphylococcal Infections/diagnosis/ epidemiology/prevention & control Staphylococcus aureus/ isolation & purification Switzerland/epidemiology Dewey 616 56 Département de médecine 221 false 526 Epidémiologie et contrôle de la résistance aux antibiotiques 866 251 Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière 330 Schweizerische medizinische Wochenschrift 132 17-18 af9a6c54-ca89-46f4-8bcd-ec20c9b9245b Article Restricted file1.pdf 513306 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de médecine

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PROJET e-LEARNING: des principes clés du développement durable à la pratique de projet		2007	478	205
Epidemiology of methicillin-resistant Staphylococcus aureus: results of a nation-wide survey in Switzerland	Schweizerische medizinische Wochenschrift	2002	642	0

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