Scientific article

Cocaine distribution in wild Erythroxylum species

Published inJournal of ethnopharmacology, vol. 103, no. 3, p. 439-447
Publication date2006

Cocaine distribution was studied in leaves of wild Erythroxylum species originating from Bolivia, Brazil, Ecuador, Paraguay, Peru, Mexico, USA, Venezuela and Mauritius. Among 51 species, 28 had never been phytochemically investigated before. Cocaine was efficiently and rapidly extracted with methanol, using focused microwaves at atmospheric pressure, and analysed without any further purification by capillary gas chromatography coupled to mass spectrometry. Cocaine was reported for the first time in 14 species. Erythroxylum laetevirens was the wild species with the highest cocaine content. Its qualitative chromatographic profile also revealed other characteristic tropane alkaloids. Finally, its cocaine content was compared to those of two cultivated coca plants as well as with a coca tea bag sample.

  • Coca/chemistry
  • Cocaine/analysis
  • Dopamine Uptake Inhibitors/analysis
  • Erythroxylaceae/chemistry/classification
  • Gas Chromatography-Mass Spectrometry
  • Mauritius
  • Microwaves
  • North America
  • Plant Leaves
  • South America
  • Tropanes/analysis
Citation (ISO format)
BIERI, Stefan et al. Cocaine distribution in wild Erythroxylum species. In: Journal of ethnopharmacology, 2006, vol. 103, n° 3, p. 439–447. doi: 10.1016/j.jep.2005.08.021
Main files (1)
Article (Published version)
ISSN of the journal0378-8741

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