UNIGE document Scientific Article
previous document  unige:6708  next document
add to browser collection
Title

Extraction and analysis of different Cannabis samples by headspace solid-phase microextraction combined with gas chromatography-mass spectrometry

Authors
Ilias, Yara
Mathieu, Patrick
Published in Journal of Separation Science. 2005, vol. 28, no. 17, p. 2293-300
Abstract A headspace solid-phase microextraction combined with GC-MS method was developed for the extraction and analysis of cannabinoids from Cannabis samples. Different commercially available fibres were evaluated; polydimethylsiloxane 100 microm was selected as the most efficient one. In order to enhance sensitivity and reduce analysis time, the sampling temperature was studied and it showed that extraction should be performed at a high temperature (150 degrees C). In relation with the high lipophilicity of cannabinoids, a relatively long desorption time (3 min) was necessary to ensure a total transfer from the fibre into the injection port of the gas chromatograph. The method was finally applied to the extraction of Swiss marijuana samples from different regions. Data treatment by principal component analysis and hierarchical cluster analysis allowed a discrimination of the different batches.
Keywords Cannabidiol/analysisCannabinoids/analysisCannabinol/analysisCannabis/chemistryCluster AnalysisGas Chromatography-Mass Spectrometry/methodsMolecular StructurePrincipal Component AnalysisSwitzerlandTetrahydrocannabinol/analysis
Identifiers
PMID: 16342794
Full text
Article (Published version) (1.2 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
ILIAS, Yara et al. Extraction and analysis of different Cannabis samples by headspace solid-phase microextraction combined with gas chromatography-mass spectrometry. In: Journal of Separation Science, 2005, vol. 28, n° 17, p. 2293-300. https://archive-ouverte.unige.ch/unige:6708

199 hits

0 download

Update

Deposited on : 2010-05-28

Export document
Format :
Citation style :