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English

Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice

Contributors

Vinet, Laurent; Lamprianou, Smaragda; Babic, Andréj; Lange, Norbert; Thorel, Fabrizio; Herrera, Pedro Luis; Montet, Xavier; Meda, Paolo

Published in

Diabetologia, vol. 58, no. 2, p. 304-312

Publication date

2015

Abstract

Non-invasive imaging of beta cells is a much-needed development but is one that faces significant biological and technological hurdles. A relevant imaging method should at least allow for an evaluation over time of the mass of beta cells under physiological and pathological conditions, and for an assessment of novel therapies. We, therefore, investigated the ability of a new MRI probe to repeatedly measure the loss of beta cells in a rodent model.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

VINET, Laurent et al. Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice. In: Diabetologia, 2015, vol. 58, n° 2, p. 304–312. doi: 10.1007/s00125-014-3442-2

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0012-186X
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351downloads

Technical informations

Creation

09/04/2015 15:31:00

First validation

09/04/2015 15:31:00

Update

14/03/2023 23:10:34

Status update

14/03/2023 23:10:34

Last indexation

30/10/2024 23:54:56
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