Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers
Published inNature, vol. 514, no. 7523, p. 503-507
Publication date2014
Abstract
Keywords
- Aging/physiology
- Animals
- Cell Dedifferentiation
- Cell Proliferation
- Cell Transdifferentiation
- Diabetes Mellitus, Experimental/pathology/therapy
- Diabetes Mellitus, Type 1/pathology/therapy
- Forkhead Transcription Factors/metabolism
- Glucagon-Secreting Cells/cytology/secretion
- Humans
- Insulin/biosynthesis/secretion
- Insulin-Secreting Cells/cytology/secretion
- Mice
- Regeneration
- Sexual Maturation
- Somatostatin/biosynthesis/secretion
- Somatostatin-Secreting Cells/cytology/secretion
Research group
Citation (ISO format)
CHERA, Simona et al. Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers. In: Nature, 2014, vol. 514, n° 7523, p. 503–507. doi: 10.1038/nature13633
Main files (1)
Article (Published version)
Identifiers
- PID : unige:55456
- DOI : 10.1038/nature13633
- PMID : 25141178
ISSN of the journal0028-0836