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Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

ContributorsSomm, Emmanuel; Larvaron, Pierre; Van De Looij, Yohan; Toulotte, Audrey; Chatagner, Alexandra; Faure, Magali; Métairon, Sylviane; Mansourian, Robert; Raymond, Frédéric; Gruetter, Rolf; Wang, Bing; Sizonenko, Stéphaneorcid; Hüppi, Petra Susan
Published inPediatric research, vol. 75, no. 1-1, p. 51-61
Publication date2014
Abstract

Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementation with bLf on IUGR-induced sequelae, including inadequate growth and altered cerebral development, remains unknown.

Keywords
  • Animals
  • Body Weight/drug effects
  • Brain/drug effects/metabolism
  • Dexamethasone/administration & dosage
  • Dietary Supplements
  • Female
  • Fetal Growth Retardation/metabolism/prevention & control
  • Gene Expression/drug effects
  • Growth/drug effects
  • Lactation
  • Lactoferrin/administration & dosage/pharmacology
  • Polymerase Chain Reaction
  • Pregnancy
  • Rats
  • Weight Gain/drug effects
Affiliation
Research group
Citation (ISO format)
SOMM, Emmanuel et al. Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism. In: Pediatric research, 2014, vol. 75, n° 1-1, p. 51–61. doi: 10.1038/pr.2013.199
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0031-3998
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