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Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain

Published inAnnals of clinical and translational neurology, vol. 1, no. 12, p. 955-967
Publication date2014
Abstract

Lactoferrin (Lf) is an iron-binding glycoprotein secreted in maternal milk presenting anti-inflammatory and antioxidant properties. It shows efficient absorption into the brain from nutritional source. Brain injury frequently resulting from cerebral hypoxia-ischemia (HI) has a high incidence in premature infants with ensuing neurodevelopmental disabilities. We investigated the neuroprotective effect of maternal nutritional supplementation with Lf during lactation in a rat model of preterm HI brain injury using magnetic resonance imaging (MRI), brain gene, and protein expression.

Citation (ISO format)
VAN DE LOOIJ, Yohan et al. Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain. In: Annals of clinical and translational neurology, 2014, vol. 1, n° 12, p. 955–967. doi: 10.1002/acn3.138
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ISSN of the journal2328-9503
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