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Title

Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain

Authors
Toulotte, Audrey
Published in Annals of Clinical and Translational Neurology. 2014, vol. 1, no. 12, p. 955-67
Abstract Lactoferrin (Lf) is an iron-binding glycoprotein secreted in maternal milk presenting anti-inflammatory and antioxidant properties. It shows efficient absorption into the brain from nutritional source. Brain injury frequently resulting from cerebral hypoxia-ischemia (HI) has a high incidence in premature infants with ensuing neurodevelopmental disabilities. We investigated the neuroprotective effect of maternal nutritional supplementation with Lf during lactation in a rat model of preterm HI brain injury using magnetic resonance imaging (MRI), brain gene, and protein expression.
Identifiers
PMID: 25574471
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Research group L'imagerie cérébrale (184)
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VAN DE LOOIJ, Yohan et al. Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain. In: Annals of Clinical and Translational Neurology, 2014, vol. 1, n° 12, p. 955-67. https://archive-ouverte.unige.ch/unige:48454

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Deposited on : 2015-03-26

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