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Title

MRI of animal models of developmental disorders and translation to human imaging

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Published in Current Opinion in Neurology. 2014, vol. 27, no. 2, p. 157-67
Abstract In order to understand the pathophysiological mechanisms leading to the specific brain alterations observed in immature newborn babies, preclinical studies on animal models mimicking clinical reality are mandatory and are ideally coupled with imaging modalities transferable to the human scenario. The availability of MRI techniques on both clinical and animal scanners allows this methodological transfer from bench to bedside. The aim of this review is to give an overview of the recent findings in MRI of animal models of developmental disorders and emphasize what we can learn from MRI on these models.
Keywords AnimalsBrain/pathology/physiopathologyDevelopmental Disabilities/diagnosisDisease Models, AnimalHumansMagnetic Resonance ImagingTranslational Medical Research
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PMID: 24556737
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Article (Published version) (4.3 MB) - document accessible for UNIGE members only Limited access to UNIGE
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Research group L'imagerie cérébrale (184)
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VAN DE LOOIJ, Yohan et al. MRI of animal models of developmental disorders and translation to human imaging. In: Current Opinion in Neurology, 2014, vol. 27, n° 2, p. 157-67. https://archive-ouverte.unige.ch/unige:48453

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Deposited on : 2015-03-26

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