en
Scientific article
Review
English

MRI of animal models of developmental disorders and translation to human imaging

Published inCurrent opinion in neurology, vol. 27, no. 2, p. 157-167
Publication date2014
Abstract

In order to understand the pathophysiological mechanisms leading to the specific brain alterations observed in immature newborn babies, preclinical studies on animal models mimicking clinical reality are mandatory and are ideally coupled with imaging modalities transferable to the human scenario. The availability of MRI techniques on both clinical and animal scanners allows this methodological transfer from bench to bedside. The aim of this review is to give an overview of the recent findings in MRI of animal models of developmental disorders and emphasize what we can learn from MRI on these models.

Keywords
  • Animals
  • Brain/pathology/physiopathology
  • Developmental Disabilities/diagnosis
  • Disease Models, Animal
  • Humans
  • Magnetic Resonance Imaging
  • Translational Medical Research
Citation (ISO format)
VAN DE LOOIJ, Yohan et al. MRI of animal models of developmental disorders and translation to human imaging. In: Current opinion in neurology, 2014, vol. 27, n° 2, p. 157–167. doi: 10.1097/WCO.0000000000000066
Main files (1)
Article (Published version)
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Identifiers
ISSN of the journal1350-7540
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