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Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE)

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Published in Methods in Molecular Biology. 2014, vol. n/a
Abstract Neuropathological techniques such as conventional and immunohistochemical staining of paraffin-embedded tissue sections are instrumental for identification and characterization of aberrations of organ architecture during human inflammatory disorders of the central nervous system (CNS) as in their animal models. Here we describe step-by-step protocols for tissue processing, sectioning, and conventional and immunohistochemical stainings to display as well as quantify CNS inflammation, demyelination, and neuronal damage in experimental autoimmune encephalomyelitis (EAE), an animal model of Multiple Sclerosis (MS).
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PMID: 25146304
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Structures
Research group La Sclérose en plaques (908)
Projects FNS: PP00P3_128372
Swiss MS Society
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STEINBACH, Karin, MERKLER, Doron. Neuropathological Techniques to Investigate CNS Pathology in Experimental Autoimmune Encephalomyelitis (EAE). In: Methods in Molecular Biology, 2014, vol. n/a. https://archive-ouverte.unige.ch/unige:45633

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Deposited on : 2015-01-20

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