en
Scientific article
Case report
English

Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter

Published inSwiss surgery, vol. 9, no. 4, p. 193-197
Publication date2003
Abstract

There is accumulating evidence, both quantitative and qualitative, that pelvic irradiation affects anorectal function. However, the molecular mechanisms responsible for radiation-induced damage to the anal sphincter remain unclear.

Keywords
  • Adenocarcinoma/radiotherapy/surgery
  • Aged
  • Aged, 80 and over
  • Anal Canal/pathology/radiation effects
  • Connective Tissue Growth Factor
  • Disease Progression
  • Fibrosis/pathology/surgery
  • Humans
  • Immediate-Early Proteins/analysis
  • Immunoenzyme Techniques
  • Intercellular Signaling Peptides and Proteins/analysis
  • Male
  • Muscle, Smooth/pathology/radiation effects
  • Neoplasms, Radiation-Induced/surgery
  • Neoplasms, Second Primary/surgery
  • Prostatic Neoplasms/radiotherapy
  • Radiation Injuries/pathology
  • Rectal Neoplasms/surgery
  • Rectum/pathology/radiation effects/surgery
  • Reoperation
  • Transforming Growth Factor beta/analysis
  • Transforming Growth Factor beta1
Citation (ISO format)
GERVAZ, Pascal et al. Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter. In: Swiss surgery, 2003, vol. 9, n° 4, p. 193–197. doi: 10.1024/1023-9332.9.4.193
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1023-9332
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