Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter

Article Article scientifique Rapport de cas Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter eng 2003 author Gervaz Pascal 565571 author Hennig R author Buechler Marco Paolo 91069 author Soravia Claudio 126700 author Brigstock D R author Morel Philippe 22337 author Egger Jean-François 93866 author Friess H 193-197 10.1024/1023-9332.9.4.193 12974179 1023-9332 There is accumulating evidence, both quantitative and qualitative, that pelvic irradiation affects anorectal function. However, the molecular mechanisms responsible for radiation-induced damage to the anal sphincter remain unclear. Adenocarcinoma/radiotherapy/surgery Aged Aged, 80 and over Anal Canal/pathology/radiation effects Connective Tissue Growth Factor Disease Progression Fibrosis/pathology/surgery Humans Immediate-Early Proteins/analysis Immunoenzyme Techniques Intercellular Signaling Peptides and Proteins/analysis Male Muscle, Smooth/pathology/radiation effects Neoplasms, Radiation-Induced/surgery Neoplasms, Second Primary/surgery Prostatic Neoplasms/radiotherapy Radiation Injuries/pathology Rectal Neoplasms/surgery Rectum/pathology/radiation effects/surgery Reoperation Transforming Growth Factor beta/analysis Transforming Growth Factor beta1 Dewey 617 57 Département de chirurgie 222 false 79 Chirurgie viscérale 104 1329 Chirurgie viscérale (HUG) Swiss surgery 9 4 3c154666-3da7-4aab-a230-51c064fdbddb Article (Published version) Restricted 20150112154703308.pdf 1513936 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de chirurgie

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Long-term expression of fibrogenic cytokines in radiation-induced damage to the internal anal sphincter	Swiss surgery			2003	738	0

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Buechler, Marco Paolo