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Title

Low-dose sufentanil does not potentiate intrathecal morphine for perioperative analgesia after major colorectal surgery

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Published in Canadian Journal of Anesthesia. 2007, vol. 54, no. 10, p. 811-7
Abstract Both intrathecal sufentanil (ITS) and intrathecal morphine (ITM) improve analgesia in obstetrical or cardiac procedures. From a pharmacokinetic standpoint, combining these two opioids may improve perioperative analgesia. We performed a prospective randomized double-blind study to compare the analgesic efficacy of ITM alone vs a mixture of a low dose of ITS plus ITM for perioperative pain relief in colorectal surgery.
Keywords AdolescentAdultAgedAged, 80 and overAnalgesia, Patient-ControlledAnalgesics, Opioid/adverse effects/therapeutic useColon/surgeryDouble-Blind MethodDrug InteractionsFemaleHumansInfusions, IntravenousMaleMiddle AgedMorphine/adverse effects/therapeutic usePain, Postoperative/drug therapyPatient SatisfactionPostoperative CareProspective StudiesRectum/surgerySufentanil/adverse effects/therapeutic use
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PMID: 17934162
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Research groups Enfants et hyperréactivité bronchique (69)
Groupe Salvodelli Georges (simulation) (878)
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CULEBRAS, Javier et al. Low-dose sufentanil does not potentiate intrathecal morphine for perioperative analgesia after major colorectal surgery. In: Canadian Journal of Anesthesia, 2007, vol. 54, n° 10, p. 811-7. https://archive-ouverte.unige.ch/unige:43101

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Deposited on : 2014-12-11

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