Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor

Planchamp Messeiller, Corinne; Gex-Fabry, Marianne; Dornier, Christophe; Quadri Defilippis, Rafael; Reist Oechslin, Marianne; Ivancevic, Marko Kresimir; Vallée, Jean-Paul; Pochon, Sibylle Carine; Terrier, François; Balant, Luc; Stieger, Bruno; Meier, Peter J; Pastor, Catherine

doi:10.1097/01.rli.0000129156.16054.30

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Title		Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor
Authors		Planchamp Messeiller, Corinne Gex-Fabry, Marianne Dornier, Christophe Quadri Defilippis, Rafael Reist Oechslin, Marianne Ivancevic, Marko Kresimir Vallée, Jean-Paul Pochon, Sibylle Carine Terrier, François Balant, Luc Stieger, Bruno Meier, Peter J Pastor, Catherine show all authors [1 - 13]
Published in		Investigative Radiology. 2004, vol. 39, no. 8, p. 506-15
Abstract		To investigate the transport of the hepatobiliary magnetic resonance (MR) imaging contrast agent Gd-BOPTA into rat hepatocytes.
Keywords		Animals — Biological Transport — Bioreactors — Contrast Media/pharmacokinetics — Gadolinium/pharmacokinetics — Gadolinium DTPA/pharmacokinetics — Hepatocytes/metabolism — Magnetic Resonance Imaging — Male — Meglumine/analogs & derivatives/pharmacokinetics — Membrane Transport Proteins/metabolism — Multidrug Resistance-Associated Proteins/metabolism — Organic Anion Transporters/metabolism — Organometallic Compounds/pharmacokinetics — Rats — Rats, Sprague-Dawley
Identifiers		DOI: 10.1097/01.rli.0000129156.16054.30 PMID: 15257212
Full text		Article (Published version) (904 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Pharmacologie et imagerie du foie (664) Imagerie cardiaque fonctionnelle (541)
Citation (ISO format)		PLANCHAMP MESSEILLER, Corinne et al. Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor. In: Investigative Radiology, 2004, vol. 39, n° 8, p. 506-15. doi: 10.1097/01.rli.0000129156.16054.30 https://archive-ouverte.unige.ch/unige:42524