Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor

Planchamp Messeiller, Corinne; Gex-Fabry, Marianne; Dornier, Christophe; Quadri Defilippis, Rafael; Reist Oechslin, Marianne; Ivancevic, Marko Kresimir; Vallée, Jean-Paul; Pochon, Sibylle Carine; Terrier, François; Balant, Luc; Stieger, Bruno; Meier, Peter J; Pastor, Catherine

doi:10.1097/01.rli.0000129156.16054.30

Scientific article

English

Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor

ContributorsPlanchamp Messeiller, Corinne; Gex-Fabry, Marianne; Dornier, Christophe; Quadri Defilippis, Rafael; Reist Oechslin, Marianne; Ivancevic, Marko Kresimir; Vallée, Jean-Paul

; Pochon, Sibylle Carine; Terrier, François; Balant, Luc; Stieger, Bruno; Meier, Peter J; Pastor, Catherine

Published inInvestigative radiology, vol. 39, no. 8, p. 506-515

Publication date2004

Abstract

To investigate the transport of the hepatobiliary magnetic resonance (MR) imaging contrast agent Gd-BOPTA into rat hepatocytes.

Keywords

Animals
Biological Transport
Bioreactors
Contrast Media/pharmacokinetics
Gadolinium/pharmacokinetics
Gadolinium DTPA/pharmacokinetics
Hepatocytes/metabolism
Magnetic Resonance Imaging
Male
Meglumine/analogs & derivatives/pharmacokinetics
Membrane Transport Proteins/metabolism
Multidrug Resistance-Associated Proteins/metabolism
Organic Anion Transporters/metabolism
Organometallic Compounds/pharmacokinetics
Rats
Rats, Sprague-Dawley

Affiliation entities

Research groups

Citation (ISO format)

PLANCHAMP MESSEILLER, Corinne et al. Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor. In: Investigative radiology, 2004, vol. 39, n° 8, p. 506–515. doi: 10.1097/01.rli.0000129156.16054.30

Article (Published version)

Identifiers

PID : unige:42524
DOI : 10.1097/01.rli.0000129156.16054.30
PMID : 15257212

Journal ISSN0020-9996

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Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor

To investigate the transport of the hepatobiliary magnetic resonance (MR) imaging contrast agent Gd-BOPTA into rat hepatocytes.

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