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Scientific article
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English

Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor

Published inInvestigative radiology, vol. 39, no. 8, p. 506-515
Publication date2004
Abstract

To investigate the transport of the hepatobiliary magnetic resonance (MR) imaging contrast agent Gd-BOPTA into rat hepatocytes.

Keywords
  • Animals
  • Biological Transport
  • Bioreactors
  • Contrast Media/pharmacokinetics
  • Gadolinium/pharmacokinetics
  • Gadolinium DTPA/pharmacokinetics
  • Hepatocytes/metabolism
  • Magnetic Resonance Imaging
  • Male
  • Meglumine/analogs & derivatives/pharmacokinetics
  • Membrane Transport Proteins/metabolism
  • Multidrug Resistance-Associated Proteins/metabolism
  • Organic Anion Transporters/metabolism
  • Organometallic Compounds/pharmacokinetics
  • Rats
  • Rats, Sprague-Dawley
Citation (ISO format)
PLANCHAMP MESSEILLER, Corinne et al. Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor. In: Investigative radiology, 2004, vol. 39, n° 8, p. 506–515. doi: 10.1097/01.rli.0000129156.16054.30
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Article (Published version)
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ISSN of the journal0020-9996
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Technical informations

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