UNIGE document Scientific Article
previous document  unige:41735  next document
add to browser collection

Annotation of glycoproteins in the SWISS-PROT database

Published in Proteomics. 2001, vol. 1, no. 2, p. 262-8
Abstract SWISS-PROT is a protein sequence database, which aims to be nonredundant, fully annotated and highly cross-referenced. Most eukaryotic gene products undergo co- and/or post-translational modifications, and these need to be included in the database in order to describe the mature protein. SWISS-PROT includes information on many types of different protein modifications. As glycosylation is the most common type of post-translational protein modification, we are currently placing an emphasis on annotation of protein glycosylation in SWISS-PROT. Information on the position of the sugar within the polypeptide chain, the reducing terminal linkage as well as additional information on biological function of the sugar is included in the database. In this paper we describe how we account for the different types of protein glycosylation, namely N-linked glycosylation, O-linked glycosylation, proteoglycans, C-linked glycosylation and the attachment of glycosyl-phosphatidylinosital anchors to proteins.
Keywords Amino Acid SequenceAnimalsBinding SitesDatabases, ProteinEukaryotic CellsGlycoproteins/chemistry/genetics/metabolismGlycosylationMolecular Sequence DataPhosphorylationProkaryotic CellsProtein Processing, Post-TranslationalProteoglycans/chemistry/genetics/metabolismProteome
PMID: 11680872
Full text
Article (Published version) (186 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research groups Calipho (80)
Swiss Institute of Bioinformatics
Swiss-Prot Research Group
(ISO format)
JUNG, Eva et al. Annotation of glycoproteins in the SWISS-PROT database. In: Proteomics, 2001, vol. 1, n° 2, p. 262-8. doi: 10.1002/1615-9861(200102)1:2<262::AID-PROT262>3.0.CO;2-# https://archive-ouverte.unige.ch/unige:41735

439 hits

0 download


Deposited on : 2014-11-12

Export document
Format :
Citation style :