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Scientific article
Open access
English

Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment

Published inBMC infectious diseases, vol. 13, 85
Publication date2013
Abstract

With declining vectorial transmission, Chagas disease predominantly affects adults nowadays. The efficacy of nifurtimox in the chronic phase in adult patients is poorly known, particularly in regions where there is no risk of reinfection. Recommendations for treatment outcome assessment rely on serological follow-up. We evaluated the serological and parasitological response to nifurtimox in a cohort of adult patients three years post-treatment in Switzerland.

Keywords
  • Adult
  • Chagas Disease/drug therapy/parasitology
  • Chronic Disease
  • Cross-Sectional Studies
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Nifurtimox/therapeutic use
  • Real-Time Polymerase Chain Reaction
  • Treatment Outcome
  • Trypanocidal Agents/therapeutic use
  • Trypanosoma cruzi/genetics/immunology
Citation (ISO format)
JACKSON, Yves-Laurent Julien et al. Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment. In: BMC infectious diseases, 2013, vol. 13, p. 85. doi: 10.1186/1471-2334-13-85
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Article (Published version)
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Identifiers
ISSN of the journal1471-2334
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222downloads

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