Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment

Article Article scientifique Article Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment eng 2013 author Jackson Yves-Laurent Julien 0000-0001-5619-333X 83989 author Chatelain Eric 533942 author Mauris Anne 24479 author Holst Marylise author Miao Qianqian author Chappuis François 34709 author Ndao Momar Diarra 824895 85 10.1186/1471-2334-13-85 23406191 1471-2334 With declining vectorial transmission, Chagas disease predominantly affects adults nowadays. The efficacy of nifurtimox in the chronic phase in adult patients is poorly known, particularly in regions where there is no risk of reinfection. Recommendations for treatment outcome assessment rely on serological follow-up. We evaluated the serological and parasitological response to nifurtimox in a cohort of adult patients three years post-treatment in Switzerland. Adult Chagas Disease/drug therapy/parasitology Chronic Disease Cross-Sectional Studies Enzyme-Linked Immunosorbent Assay Female Follow-Up Studies Humans Male Middle Aged Nifurtimox/therapeutic use Real-Time Polymerase Chain Reaction Treatment Outcome Trypanocidal Agents/therapeutic use Trypanosoma cruzi/genetics/immunology Dewey 613 64 Département de santé et médecine communautaires 22A false 16 Groupe Jean-Michel Gaspoz 23 BMC infectious diseases 13 144304f8-4644-4c7d-82c6-57b9d10a331a Article (Published version) Public Yves Jackson_2013_BMC Infectious Diseases.pdf 173047 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires

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Serological and parasitological response in chronic Chagas patients 3 years after nifurtimox treatment	BMC infectious diseases			2013	641	415

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