Kinetics of gadobenate dimeglumine in isolated perfused rat liver: MR imaging evaluation

Pastor, Catherine; Planchamp Messeiller, Corinne; Pochon, Sibylle Carine; Lorusso, Vito; Montet, Xavier Cédric Rodolphe; Mayer, Joachim; Terrier, François; Vallée, Jean-Paul

doi:10.1148/radiol.2291020726

Scientific article

English

Kinetics of gadobenate dimeglumine in isolated perfused rat liver: MR imaging evaluation

ContributorsPastor, Catherine

; Planchamp Messeiller, Corinne; Pochon, Sibylle Carine; Lorusso, Vito; Montet, Xavier Cédric Rodolphe; Mayer, Joachim; Terrier, François; Vallée, Jean-Paul

Published inRadiology, vol. 229, no. 1, p. 119-125

Publication date2003

Abstract

To compare in the entire liver, the hepatic kinetics of gadobenate dimeglumine (Gd-BOPTA) and gadopentetate dimeglumine (Gd-DTPA) and to evaluate the hepatic transport of Gd-BOPTA.

Keywords

Animals
Biological Transport
Contrast Media/pharmacokinetics/pharmacology
Gadolinium/diagnostic use/pharmacokinetics/pharmacology
Gadolinium DTPA/diagnostic use/pharmacokinetics/pharmacology
Liver/anatomy & histology/metabolism
Magnetic Resonance Imaging
Male
Meglumine/analogs & derivatives/diagnostic use/pharmacokinetics/pharmacology
Organometallic Compounds/diagnostic use/pharmacokinetics/pharmacology
Oxygen Consumption/drug effects
Portal Pressure/drug effects
Rats
Rats, Sprague-Dawley
Sulfobromophthalein/pharmacokinetics/pharmacology

Affiliation

Research group

Citation (ISO format)

PASTOR, Catherine et al. Kinetics of gadobenate dimeglumine in isolated perfused rat liver: MR imaging evaluation. In: Radiology, 2003, vol. 229, n° 1, p. 119–125. doi: 10.1148/radiol.2291020726

Article (Published version)

Identifiers

PID : unige:40328
DOI : 10.1148/radiol.2291020726
PMID : 12944603

ISSN of the journal0033-8419

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Kinetics of gadobenate dimeglumine in isolated perfused rat liver: MR imaging evaluation

To compare in the entire liver, the hepatic kinetics of gadobenate dimeglumine (Gd-BOPTA) and gadopentetate dimeglumine (Gd-DTPA) and to evaluate the hepatic transport of Gd-BOPTA.

Technical informations