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Title

Quantification of Gd-BOPTA uptake and biliary excretion from dynamic magnetic resonance imaging in rat livers: model validation with 153Gd-BOPTA.
Authors
Planchamp, Corinne
Pastor, Catherine
Balant, Luc
Becker, Christoph
Terrier, François
Gex-Fabry, Marianne
Published in Investigative radiology. 2005, vol. 40, no. 11, p. 705-14
Abstract We sought to develop and validate a pharmacokinetic model allowing description of the magnetic resonance (MR) signal intensity induced by the hepatobiliary contrast agent Gd-BOPTA and to quantify the overall Gd-BOPTA transport in rat liver.
Keywords Animals — Bile/metabolism — Biological Transport — Contrast Media/pharmacokinetics — Extracellular Space/metabolism — Gadolinium DTPA/pharmacokinetics — Liver/metabolism — Magnetic Resonance Imaging — Meglumine/analogs & derivatives/pharmacokinetics — Models, Biological — Organometallic Compounds/pharmacokinetics — Perfusion — Rats — Rats, Sprague-Dawley — Reproducibility of Results
Identifiers
PMID: 16230903
Full text
Article (Published version) (781 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group Pharmacologie et imagerie du foie (664)
Project
Swiss National Science Foundation: 3200-100868
Citation
(ISO format) 		PLANCHAMP, Corinne et al. Quantification of Gd-BOPTA uptake and biliary excretion from dynamic magnetic resonance imaging in rat livers: model validation with 153Gd-BOPTA. In: Investigative radiology, 2005, vol. 40, n° 11, p. 705-14. doi: 10.1097/01.rli.0000183053.08921.2b https://archive-ouverte.unige.ch/unige:40291

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Deposited on : 2014-09-18

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