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Quantification of Gd-BOPTA uptake and biliary excretion from dynamic magnetic resonance imaging in rat livers: model validation with 153Gd-BOPTA. |
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Published in | Investigative radiology. 2005, vol. 40, no. 11, p. 705-14 | |
Abstract | We sought to develop and validate a pharmacokinetic model allowing description of the magnetic resonance (MR) signal intensity induced by the hepatobiliary contrast agent Gd-BOPTA and to quantify the overall Gd-BOPTA transport in rat liver. | |
Keywords | Animals — Bile/metabolism — Biological Transport — Contrast Media/pharmacokinetics — Extracellular Space/metabolism — Gadolinium DTPA/pharmacokinetics — Liver/metabolism — Magnetic Resonance Imaging — Meglumine/analogs & derivatives/pharmacokinetics — Models, Biological — Organometallic Compounds/pharmacokinetics — Perfusion — Rats — Rats, Sprague-Dawley — Reproducibility of Results | |
Identifiers | PMID: 16230903 | |
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Research group | Pharmacologie et imagerie du foie (664) | |
Project | Swiss National Science Foundation: 3200-100868 | |
Citation (ISO format) | PLANCHAMP, Corinne et al. Quantification of Gd-BOPTA uptake and biliary excretion from dynamic magnetic resonance imaging in rat livers: model validation with 153Gd-BOPTA. In: Investigative radiology, 2005, vol. 40, n° 11, p. 705-14. doi: 10.1097/01.rli.0000183053.08921.2b https://archive-ouverte.unige.ch/unige:40291 |