UNIGE document Scientific Article
previous document  unige:39805  next document
add to browser collection
Title

Non-squamous cell neoplasms of the larynx: radiologic-pathologic correlation

Authors
Dulgerov, P
Zbären, P
Rüfenacht, D
show hidden authors show all authors [1 - 9]
Published in Radiographics. 1998, vol. 18, no. 5, p. 1189-209
Abstract A variety of benign and malignant non-squamous cell neoplasms may affect the larynx. Most of these uncommon laryngeal neoplasms are located beneath an intact mucosa, making diagnosis difficult with endoscopy alone, and sampling errors may occur if only traditional superficial biopsies are performed. In some laryngeal neoplasms, radiologic evaluation allows the correct diagnosis. Hemangiomas have very high signal intensity at T2-weighted magnetic resonance (MR) imaging and strong enhancement at both computed tomography (CT) and MR imaging after administration of contrast material. Phleboliths, which are pathognomonic for hemangiomas, are easily identified at CT. Chondrogenic tumors typically manifest with coarse or stippled calcifications at CT. Because of their high water content, chondrogenic tumors have very high signal intensity on T2-weighted MR images, whereas only moderate enhancement is observed after administration of contrast material. Lipomas typically manifest at both CT and MR imaging as homogeneous nonenhancing lesions. They are isoattenuating to subcutaneous fat at CT and isointense relative to subcutaneous fat with all MR pulse sequences. Metastases from renal adenocarcinoma typically demonstrate strong contrast enhancement and flow voids at MR imaging, and metastases from melanotic melanoma usually have high signal intensity on T1-weighted MR images and low signal intensity on T2-weighted images owing to the paramagnetic properties of melanin. Although radiologic findings are nonspecific in most other non-squamous cell neoplasms of the larynx (eg, Kaposi sarcoma, hematopoietic tumors, tumors of the minor salivary glands, metastases from amelanotic melanoma), cross-sectional imaging can play an important role in the diagnostic work-up of these unusual tumors by delineating the extent of submucosal tumor spread and directing the endoscopist to the appropriate site for the deep, transmucosal biopsies needed to establish the diagnosis. In addition, CT and MR imaging are crucial for posttherapeutic monitoring and early detection of local recurrence.
Keywords Carcinoma, Squamous CellFemaleHumansLaryngeal Neoplasms/pathology/radiography/secondaryLarynx/pathologyMagnetic Resonance ImagingMaleMiddle AgedSalivary Gland Neoplasms/pathology/radiographySalivary Glands, MinorTomography, X-Ray Computed
Identifiers
PMID: 9747615
Full text
Article (Published version) (3.4 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Groupe Becker Minerva (imagerie ORL) (683)
Citation
(ISO format)
BECKER, Minerva et al. Non-squamous cell neoplasms of the larynx: radiologic-pathologic correlation. In: Radiographics, 1998, vol. 18, n° 5, p. 1189-209. doi: 10.1148/radiographics.18.5.9747615 https://archive-ouverte.unige.ch/unige:39805

442 hits

0 download

Update

Deposited on : 2014-08-27

Export document
Format :
Citation style :