β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

Halban, Philippe A.; Polonsky, Kenneth S; Bowden, Donald W; Hawkins, Meredith A; Ling, Charlotte; Mather, Kieren J; Powers, Alvin C; Rhodes, Christopher J; Sussel, Lori; Weir, Gordon C

doi:10.2337/dc14-0396

Scientific article

English

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

ContributorsHalban, Philippe A.; Polonsky, Kenneth S; Bowden, Donald W; Hawkins, Meredith A; Ling, Charlotte; Mather, Kieren J; Powers, Alvin C; Rhodes, Christopher J; Sussel, Lori; Weir, Gordon C

Published inDiabetes care, vol. 37, no. 6, p. 1751-1758

Publication date2014

Abstract

This article examines the foundation of β-cell failure in type 2 diabetes (T2D) and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment.

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement

Research groups

Fonction de l'îlot de Langerhans (324)

Citation (ISO format)

HALBAN, Philippe A. et al. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. In: Diabetes care, 2014, vol. 37, n° 6, p. 1751–1758. doi: 10.2337/dc14-0396

Article (Accepted version)

Identifiers

PID : unige:39385
DOI : 10.2337/dc14-0396
PMID : 24812433

Journal ISSN0149-5992

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Creation12/08/2014 11:59:00

First validation12/08/2014 11:59:00

Update time14/03/2023 21:31:13

Status update14/03/2023 21:31:12

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β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

This article examines the foundation of β-cell failure in type 2 diabetes (T2D) and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment.

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