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Title

CD74: a new prognostic factor for patients with malignant pleural mesothelioma
Authors
Otterstrom, Claire
Soltermann, Alex
Opitz, I
Felley-Bosco, E
Weder, W
Stahel, R A
Triponez, Frédéric
Robert, John
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Published in British Journal of Cancer. 2014, vol. 110, no. 8, p. 2040-6
Abstract The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS).
Keywords Aged — Antigens, Differentiation, B-Lymphocyte/biosynthesis/genetics — Calbindin 2/biosynthesis — Female — Gene Expression Regulation, Neoplastic — Histocompatibility Antigens Class II/biosynthesis/genetics — Humans — Intramolecular Oxidoreductases/biosynthesis — Lung Neoplasms/genetics/pathology — Macrophage Migration-Inhibitory Factors/biosynthesis — Male — Mesothelioma/genetics/pathology — Middle Aged — PTEN Phosphohydrolase/biosynthesis — Prognosis — Tissue Array Analysis — Tumor Markers, Biological/biosynthesis/genetics
Identifiers
PMID: 24594996
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Structures
Faculté de médecine / Section de médecine clinique / Département de chirurgie
Research group Mésothéliome pleural malin (944)
Citation
(ISO format) 		OTTERSTROM, Claire et al. CD74: a new prognostic factor for patients with malignant pleural mesothelioma. In: British Journal of Cancer, 2014, vol. 110, n° 8, p. 2040-6. https://archive-ouverte.unige.ch/unige:39214

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Deposited on : 2014-08-06

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