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Scientific Article
unige:39214 
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CD74: a new prognostic factor for patients with malignant pleural mesothelioma |
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| Published in | British journal of cancer. 2014, vol. 110, no. 8, p. 2040-6 | |
| Abstract | The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS). | |
| Keywords | Aged — Antigens, Differentiation, B-Lymphocyte/biosynthesis/genetics — Calbindin 2/biosynthesis — Female — Gene Expression Regulation, Neoplastic — Histocompatibility Antigens Class II/biosynthesis/genetics — Humans — Intramolecular Oxidoreductases/biosynthesis — Lung Neoplasms/genetics/pathology — Macrophage Migration-Inhibitory Factors/biosynthesis — Male — Mesothelioma/genetics/pathology — Middle Aged — PTEN Phosphohydrolase/biosynthesis — Prognosis — Tissue Array Analysis — Tumor Markers, Biological/biosynthesis/genetics | |
| Identifiers | DOI: 10.1038/bjc.2014.117 PMID: 24594996 | |
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| Research group | Cancer du poumon et mésothéliome pleural malin (944) | |
| Citation (ISO format) | OTTERSTROM, Claire et al. CD74: a new prognostic factor for patients with malignant pleural mesothelioma. In: British journal of cancer, 2014, vol. 110, n° 8, p. 2040-6. doi: 10.1038/bjc.2014.117 https://archive-ouverte.unige.ch/unige:39214 |
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