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Title

CD74: a new prognostic factor for patients with malignant pleural mesothelioma

Authors
Opitz, I
Felley-Bosco, E
Weder, W
Stahel, R A
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Published in British Journal of Cancer. 2014, vol. 110, no. 8, p. 2040-6
Abstract The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS).
Keywords AgedAntigens, Differentiation, B-Lymphocyte/biosynthesis/geneticsCalbindin 2/biosynthesisFemaleGene Expression Regulation, NeoplasticHistocompatibility Antigens Class II/biosynthesis/geneticsHumansIntramolecular Oxidoreductases/biosynthesisLung Neoplasms/genetics/pathologyMacrophage Migration-Inhibitory Factors/biosynthesisMaleMesothelioma/genetics/pathologyMiddle AgedPTEN Phosphohydrolase/biosynthesisPrognosisTissue Array AnalysisTumor Markers, Biological/biosynthesis/genetics
Identifiers
PMID: 24594996
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Structures
Research group Mésothéliome pleural malin (944)
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(ISO format)
OTTERSTROM, Claire et al. CD74: a new prognostic factor for patients with malignant pleural mesothelioma. In: British Journal of Cancer, 2014, vol. 110, n° 8, p. 2040-6. https://archive-ouverte.unige.ch/unige:39214

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Deposited on : 2014-08-06

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