en
Scientific article
English

CD74: a new prognostic factor for patients with malignant pleural mesothelioma

Published inBritish journal of cancer, vol. 110, no. 8, p. 2040-2046
Publication date2014
Abstract

The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS).

Keywords
  • Aged
  • Antigens, Differentiation, B-Lymphocyte/biosynthesis/genetics
  • Calbindin 2/biosynthesis
  • Female
  • Gene Expression Regulation, Neoplastic
  • Histocompatibility Antigens Class II/biosynthesis/genetics
  • Humans
  • Intramolecular Oxidoreductases/biosynthesis
  • Lung Neoplasms/genetics/pathology
  • Macrophage Migration-Inhibitory Factors/biosynthesis
  • Male
  • Mesothelioma/genetics/pathology
  • Middle Aged
  • PTEN Phosphohydrolase/biosynthesis
  • Prognosis
  • Tissue Array Analysis
  • Tumor Markers, Biological/biosynthesis/genetics
Citation (ISO format)
OTTERSTROM, Claire et al. CD74: a new prognostic factor for patients with malignant pleural mesothelioma. In: British journal of cancer, 2014, vol. 110, n° 8, p. 2040–2046. doi: 10.1038/bjc.2014.117
Main files (1)
Article (Published version)
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Identifiers
ISSN of the journal0007-0920
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3downloads

Technical informations

Creation08/04/2014 3:42:00 PM
First validation08/04/2014 3:42:00 PM
Update time03/14/2023 9:30:27 PM
Status update03/14/2023 9:30:27 PM
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