CD74: a new prognostic factor for patients with malignant pleural mesothelioma

Article Article scientifique Article CD74: a new prognostic factor for patients with malignant pleural mesothelioma eng 2014 author Otterstrom Claire 658759 author Soltermann Alex 129425 author Opitz I author Felley-Bosco E author Weder W author Stahel R A author Triponez Frédéric 28673 author Robert John 55421 author Serre Beinier Véronique 0000-0002-6016-1645 123229 2040-2046 10.1038/bjc.2014.117 24594996 0007-0920 The pro-inflammatory cytokine migration inhibitory factor (MIF) and its receptor CD74 have been proposed as possible therapeutic targets in several cancers. We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS). Aged Antigens, Differentiation, B-Lymphocyte/biosynthesis/genetics Calbindin 2/biosynthesis Female Gene Expression Regulation, Neoplastic Histocompatibility Antigens Class II/biosynthesis/genetics Humans Intramolecular Oxidoreductases/biosynthesis Lung Neoplasms/genetics/pathology Macrophage Migration-Inhibitory Factors/biosynthesis Male Mesothelioma/genetics/pathology Middle Aged PTEN Phosphohydrolase/biosynthesis Prognosis Tissue Array Analysis Tumor Markers, Biological/biosynthesis/genetics Dewey 617 57 Département de chirurgie 222 false 902 Cancer du poumon et mésothéliome pleural malin 944 British journal of cancer 110 8 21b39fa3-01b5-4232-b79b-4b1495dc1a8e Article (Published version) Restricted bjc2014117a.pdf 958040 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de chirurgie

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CD74: a new prognostic factor for patients with malignant pleural mesothelioma	British journal of cancer			2014	578	3

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Otterstrom, Claire