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Title

Percutaneous treatment of liver tumors with an adapted probe for cooled-tip, impedance-controlled radio-frequency ablation under open-magnet MR guidance: initial results

Authors
Kelekis, Alexis
Roggan, André
Published in European Radiology. 2003, vol. 13, no. 5, p. 1100-5
Abstract Percutaneous radio-frequency (RF) ablation of liver tumors is usually performed under guidance of real-time US, but some tumor nodules in some patients cannot be adequately visualized with this technique. We report our preliminary results with an MR-compatible, internally perfused 17-G RF probe adapted to a standard RF generator for impedance-controlled RF ablation under MR guidance. Following initial testing of the probe for MR compatibility, artifacts and macroscopic effects on an ex vivo pig liver, four patients with eight neoplastic liver nodules (five metastatic and three primary), which could not be properly targeted by US, were treated with the cooled-tip technique under MRI guidance in an open 0.23-T magnet. Metallic artifacts produced by the probe were useful for accurate placement and did not interfere with MRI monitoring at the end of the procedure. Based on imaging findings, the immediate result of RF was considered adequate in all instances. Local recurrence occurred in one instance after 6 months, requiring repeat treatment. No adverse effects were noted. Initial experience suggests that the probe we used allows to perform impedance-controlled cooled-tip RF ablation of liver tumors under open-magnet MR guidance.
Keywords AdultAgedArtifactsCarcinoma, Hepatocellular/diagnosis/pathology/surgeryCatheter Ablation/instrumentationCold TemperatureColorectal Neoplasms/diagnosis/secondary/surgeryContrast MediaElectric ImpedanceElectrocoagulationEquipment DesignFemaleFollow-Up StudiesHumansLiver Neoplasms/diagnosis/pathology/surgeryMagnetic Resonance Imaging/methodsMaleNecrosisNeoplasm Recurrence, Local/diagnosis/pathology/surgerySurgery, Computer-AssistedTomography, X-Ray ComputedTreatment Outcome
Identifiers
PMID: 12695834
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Structures
Research groups Hépatologie chirurgicale (327)
Groupe Roth Arnaud (oncologie) (285)
Imagerie et radiologie interventionnelle du foie, des voies biliaires et du pancréas (316)
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(ISO format)
KELEKIS, Alexis et al. Percutaneous treatment of liver tumors with an adapted probe for cooled-tip, impedance-controlled radio-frequency ablation under open-magnet MR guidance: initial results. In: European Radiology, 2003, vol. 13, n° 5, p. 1100-5. https://archive-ouverte.unige.ch/unige:37170

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Deposited on : 2014-06-04

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