We report experimental distribution of time-bin entangled qubits over 50 km of optical fibers. Using actively stabilized preparation and measurement devices we demonstrate violation of the Clauser-Horne-Shimony-Holt Bell inequality by more than 15 standard deviations without removing the detector noise. In addition we report a proof-of principle experiment of quantum key distribution over 50 km of optical fibers using entangled photon.