Mass spectrometry in high-throughput proteomics: ready for the big time

Nilsson, Tommy; Mann, Matthias; Aebersold, Ruedi; Yates, John R (3rd); Bairoch, Amos Marc; Bergeron, John J M

doi:10.1038/nmeth0910-681

Article scientifique

Anglais

Mass spectrometry in high-throughput proteomics: ready for the big time

Contributeurs/tricesNilsson, Tommy; Mann, Matthias; Aebersold, Ruedi; Yates, John R (3rd); Bairoch, Amos Marc

; Bergeron, John J M

Publié dansNature methods, vol. 7, no. 9, p. 681-685

Date de publication2010

Résumé

Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success.

Mots-clés

Databases, Protein
Humans
Mass Spectrometry/trends
Proteome/analysis
Proteomics/methods
Quality Control
Reproducibility of Results
Sensitivity and Specificity

Structure d'affiliation

Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique

Groupe de recherche

Calipho (80)

Citation (format ISO)

NILSSON, Tommy et al. Mass spectrometry in high-throughput proteomics: ready for the big time. In: Nature methods, 2010, vol. 7, n° 9, p. 681–685. doi: 10.1038/nmeth0910-681

Article (Published version)

Identifiants

PID : unige:36263
DOI : 10.1038/nmeth0910-681
PMID : 20805795

ISSN du journal1548-7091

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Mass spectrometry in high-throughput proteomics: ready for the big time

Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success.

Informations techniques