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Title

Administration d’albumine lors de paracentèse évacuatrice dans la cirrhose : dogme ou évidence ?
Authors
Manzocchi Besson, Sara
Nendaz, Mathieu
Spahr, Laurent François Joséph
Published in Revue médicale suisse. 2012, vol. 8, no. 358, p. 1956,1958-60
Abstract Large-volume paracentesis is the procedure of choice for refractory or symptomatic ascitis. However, there is a risk for Post-paracentesis Circulatory Dysfunction (PCD) leading to hyponatremia, renal failure, or worsening portal hypertension. PCD may be effectively prevented by volume expanders, essentially albumin, administered during and after the procedure, but the data regarding the impact of this treatment on mortality are still limited. For this reason, there is a debate about the true clinical benefit of preventing PCD, explaining some variations among published guidelines. The efficacy of molecules other than albumin is still under study but none has shown real superiority so far.
Keywords Albumins/therapeutic use — Ascites/etiology/therapy — Cardiovascular Diseases/prevention & control — Humans — Liver Cirrhosis/complications — Paracentesis/adverse effects
Identifiers
PMID: 23198648
Full text
Article (Published version) (543 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://rms.medhyg.ch/numero-358-page-1956.htm
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Faculté de médecine / Section de médecine clinique / Département de médecine interne générale, de réhabilitation et de gériatrie
Faculté de médecine / Unité de développement et de recherche en éducation médicale
Research group Acquisition de l'expertise médicale (662)
Citation
(ISO format) 		MANZOCCHI BESSON, Sara, NENDAZ, Mathieu, SPAHR, Laurent François Joséph. Administration d’albumine lors de paracentèse évacuatrice dans la cirrhose : dogme ou évidence ?. In: Revue médicale suisse, 2012, vol. 8, n° 358, p. 1956,1958-60. https://archive-ouverte.unige.ch/unige:35355

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Deposited on : 2014-04-04

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