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Administration d’albumine lors de paracentèse évacuatrice dans la cirrhose : dogme ou évidence ?

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Published in Revue médicale suisse. 2012, vol. 8, no. 358, p. 1956,1958-60
Abstract Large-volume paracentesis is the procedure of choice for refractory or symptomatic ascitis. However, there is a risk for Post-paracentesis Circulatory Dysfunction (PCD) leading to hyponatremia, renal failure, or worsening portal hypertension. PCD may be effectively prevented by volume expanders, essentially albumin, administered during and after the procedure, but the data regarding the impact of this treatment on mortality are still limited. For this reason, there is a debate about the true clinical benefit of preventing PCD, explaining some variations among published guidelines. The efficacy of molecules other than albumin is still under study but none has shown real superiority so far.
Keywords Albumins/therapeutic useAscites/etiology/therapyCardiovascular Diseases/prevention & controlHumansLiver Cirrhosis/complicationsParacentesis/adverse effects
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PMID: 23198648
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Other version: http://rms.medhyg.ch/numero-358-page-1956.htm
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Research group Acquisition de l'expertise médicale (662)
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MANZOCCHI, Sara, NENDAZ, Mathieu, SPAHR, Laurent François Joséph. Administration d’albumine lors de paracentèse évacuatrice dans la cirrhose : dogme ou évidence ?. In: Revue médicale suisse, 2012, vol. 8, n° 358, p. 1956,1958-60. https://archive-ouverte.unige.ch/unige:35355

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Deposited on : 2014-04-04

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