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Scientific article
English

Phase 2 trial of single-agent everolimus in chemotherapy-naive patients with castration-resistant prostate cancer (SAKK 08/08)

Published inEuropean urology, vol. 64, no. 1, p. 150-158
Publication date2013
Abstract

The phosphatase and tensin homolog (PTEN) tumor suppressor gene is deregulated in many advanced prostate cancers, leading to activation of the phosphatidylinositol 3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) pathway and thus increased cell survival.

Citation (ISO format)
TEMPLETON, Arnoud J et al. Phase 2 trial of single-agent everolimus in chemotherapy-naive patients with castration-resistant prostate cancer (SAKK 08/08). In: European urology, 2013, vol. 64, n° 1, p. 150–158. doi: 10.1016/j.eururo.2013.03.040
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ISSN of the journal0302-2838
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Creation12/12/2013 10:40:00 PM
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Update time03/14/2023 8:54:35 PM
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