PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice
ContributorsIglesias, José; Barg, Sebastian; Vallois, David; Lahiri, Shawon; Roger, Catherine; Yessoufou, Akadiri; Pradevand, Sylvain; McDonald, Angela; Bonal, Claire; Reimann, Frank; Gribble, Fiona; Debril, Marie-Bernard; Metzger, Daniel; Chambon, Pierre; Herrera, Pedro Luis ; Rutter, Guy A; Prentki, Marc; Thorens, Bernard; Wahli, Walter
Published inThe Journal of clinical investigation, vol. 122, no. 11, p. 4105-4117
Publication date2012
Abstract
Keywords
- Actins/genetics/metabolism
- Animals
- Exocytosis/physiology
- Female
- Gene Expression Profiling
- Glucose/genetics/metabolism
- Golgi Apparatus/genetics/metabolism
- Insulin/genetics/secretion
- Insulin-Secreting Cells/cytology/secretion
- Male
- Mice
- Mice, Mutant Strains
- PPAR delta/genetics/metabolism
- PPAR-beta/genetics/metabolism
- Protein Kinase C/genetics/metabolism
Affiliation entities
Research groups
Citation (ISO format)
IGLESIAS, José et al. PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice. In: The Journal of clinical investigation, 2012, vol. 122, n° 11, p. 4105–4117. doi: 10.1172/JCI42127
Main files (1)
Article (Published version)
Identifiers
- PID : unige:32137
- DOI : 10.1172/JCI42127
- PMID : 23093780
Journal ISSN0021-9738