• Home
Scientific article
English

Expression of metalloproteinases 1, 2, 7, 9, and 12 in human cytotrophoblastic cells from normal and preeclamptic placentas

ContributorsCohen, Marie-Benoîteorcid; Ribaux, Pascale Garlonne; Epiney, Emmanuela; Irion, Olivier
Published inNeuro-endocrinology letters, vol. 33, no. 4, p. 406-411
Publication date2012
Abstract

Preeclampsia is a specific pregnancy disorder which could be due, at least in part, to impaired invasion of trophoblastic cells. Since matrix metalloproteinases (MMPs) are the predominant proteases involved in trophoblastic invasion, we investigated and compared expression of MMP-1, 2, 7, 9 and 12 of cytotrophoblastic cells (CTB) purified from preeclamptic (PE) placentas to control CTB.

Keywords
  • Cells, Cultured
  • Female
  • Humans
  • Metalloproteases/classification/genetics/metabolism
  • Placenta/enzymology
  • Pre-Eclampsia/enzymology/physiopathology
  • Pregnancy
  • Pregnancy Trimester, Third/metabolism
  • RNA, Messenger/analysis
  • Trophoblasts/enzymology
Affiliation entities
Research groups
Citation (ISO format)
COHEN, Marie-Benoîte et al. Expression of metalloproteinases 1, 2, 7, 9, and 12 in human cytotrophoblastic cells from normal and preeclamptic placentas. In: Neuro-endocrinology letters, 2012, vol. 33, n° 4, p. 406–411.
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Additional URL for this publicationhttp://www.nel.edu/expression-of-metalloproteinases-1-2-7-9-and-12-in-human-cytotrophoblastic-cells-from-normal-and-preeclamptic-placentas-712/
Journal ISSN0172-780X
556views
0downloads

Technical informations

Creation28/10/2013 15:39:00
First validation28/10/2013 15:39:00
Update time14/03/2023 20:42:01
Status update14/03/2023 20:42:00
Last indexation30/10/2024 15:17:04
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack