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Scientific article
English

Expression of metalloproteinases 1, 2, 7, 9, and 12 in human cytotrophoblastic cells from normal and preeclamptic placentas

Published inNeuro-endocrinology letters, vol. 33, no. 4, p. 406-411
Publication date2012
Abstract

Preeclampsia is a specific pregnancy disorder which could be due, at least in part, to impaired invasion of trophoblastic cells. Since matrix metalloproteinases (MMPs) are the predominant proteases involved in trophoblastic invasion, we investigated and compared expression of MMP-1, 2, 7, 9 and 12 of cytotrophoblastic cells (CTB) purified from preeclamptic (PE) placentas to control CTB.

Keywords
  • Cells, Cultured
  • Female
  • Humans
  • Metalloproteases/classification/genetics/metabolism
  • Placenta/enzymology
  • Pre-Eclampsia/enzymology/physiopathology
  • Pregnancy
  • Pregnancy Trimester, Third/metabolism
  • RNA, Messenger/analysis
  • Trophoblasts/enzymology
Citation (ISO format)
COHEN, Marie-Benoîte et al. Expression of metalloproteinases 1, 2, 7, 9, and 12 in human cytotrophoblastic cells from normal and preeclamptic placentas. In: Neuro-endocrinology letters, 2012, vol. 33, n° 4, p. 406–411.
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0172-780X
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