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Involvement of membrane GRP78 in trophoblastic cell fusion

ContributorsFradet, Sarah; Pierredon, Sandra; Ribaux, Pascale Garlonne; Epiney, Manuela; Shin Ya, Kazuo; Irion, Olivier; Cohen, Marie-Benoîteorcid
Published inPloS one, vol. 7, no. 8, e40596
Publication date2012
Abstract

Glucose-regulated protein 78 (GRP78) is highly expressed in first trimester cytrophoblastic cells (CTBs), especially in syncytiotrophoblast (STB). However, the role of GRP78 in these cells has never been investigated.

Keywords
  • Adult
  • Cell Fusion
  • Cell Line, Tumor
  • Chorionic Gonadotropin/secretion
  • Down-Regulation/drug effects
  • Female
  • Forskolin/pharmacology
  • Heat-Shock Proteins/genetics/metabolism
  • Humans
  • Pre-Eclampsia/genetics/metabolism/pathology
  • Pregnancy
  • Pregnancy Trimester, First/genetics/metabolism
  • Trophoblasts/cytology/drug effects/metabolism/pathology
Affiliation
Research group
Citation (ISO format)
FRADET, Sarah et al. Involvement of membrane GRP78 in trophoblastic cell fusion. In: PloS one, 2012, vol. 7, n° 8, p. e40596. doi: 10.1371/journal.pone.0040596
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Article (Published version)
accessLevelPublic CC BY
Identifiers
ISSN of the journal1932-6203
611views
323downloads

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