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Initial cord blood unit volume affects mononuclear cell and CD34+ cell-processing efficiency in a non-linear fashion

ContributorsMeyer-Monard, Sandrine; Tichelli, André; Troeger, Carolyn; Arber, Caroline; de Faveri, Grazia Nicoloso; Gratwohl, Alois; Roosnek, Eddy Emile; Surbek, Daniel; Chalandon, Yves; Irion, Olivier; Castelli, Damiano; Passweg, Jakob; Kindler, Vincent Lucien
Published inCytotherapy, vol. 14, no. 2, p. 215-222
Publication date2012
Abstract

Umbilical cord blood (UCB) is a source of hematopoietic stem cells that initially was used exclusively for the hematopoietic reconstitution of pediatric patients. It is now suggested for use for adults as well, a fact that increases the pressure to obtain units with high cellularity. Therefore, the optimization of UCB processing is a priority.

Keywords
  • Antigens, CD34/immunology
  • Blood Sedimentation
  • Cell Culture Techniques/methods
  • Fetal Blood/cytology
  • Hematopoietic Stem Cells/cytology
  • Hetastarch/chemistry
  • Humans
  • Leukocytes, Mononuclear/cytology
  • T-Lymphocytes/cytology/immunology
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Research groups
Citation (ISO format)
MEYER-MONARD, Sandrine et al. Initial cord blood unit volume affects mononuclear cell and CD34+ cell-processing efficiency in a non-linear fashion. In: Cytotherapy, 2012, vol. 14, n° 2, p. 215–222. doi: 10.3109/14653249.2011.634404
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accessLevelRestricted
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Journal ISSN1465-3249
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