The evaluation of cerebral hemodynamics has been a challenge for researchers and medical professionals, particularly in the study of intracranial aneurysms. In contrast to high-quality anatomical imaging, hemodynamic and functional assessments are immature and imprecise. We are describing a series of experimental and clinical studies focusing on the assessment of the intracranial hemodynamics in a context of IAs using different modalities like: computational flow dynamics, transcranial Doppler and digital subtracted angiography. We report form the most experimental assessment and the technical challenges that it could present to the latest clinical application of the flow assessment in clinical patients. The translational link between the experimental to the clinical work is clear and necessary because in both ways validation is required and necessary. We present different experiments and studies on the domains of fluids and vascular science to determine the results and propose recommendations to facilitate a better understanding of the subject.