Scientific article
Open access

Prevention of airway hyperresponsiveness induced by left ventricular dysfunction in rats

Published inRespiratory research, vol. 13, no. december, 114
Publication date2012

The effectiveness of strategies for treatment of the altered static lung volume and against the development of bronchial hyperreactivity (BHR) following a left ventricular dysfunction (LVD) induced by myocardial ischaemia was investigated in a rat model of sustained postcapillary pulmonary hypertension.

  • Airway Resistance/drug effects
  • Angiotensin-Converting Enzyme Inhibitors/pharmacology
  • Animals
  • Arterial Pressure/drug effects
  • Bronchial Hyperreactivity/etiology/physiopathology/prevention & control
  • Bronchial Provocation Tests
  • Bronchoconstrictor Agents/administration & dosage
  • Calcium Channel Blockers/pharmacology
  • Disease Models, Animal
  • Diuretics/pharmacology
  • Drug Therapy, Combination
  • Hypertension, Pulmonary/drug therapy/etiology/physiopathology
  • Lung/drug effects/physiopathology
  • Lung Volume Measurements
  • Male
  • Methacholine Chloride/adverse effects
  • Myocardial Ischemia/complications
  • Plethysmography
  • Pulmonary Artery/drug effects/physiopathology
  • Rats
  • Rats, Sprague-Dawley
  • Time Factors
  • Ventricular Dysfunction, Left/drug therapy/etiology/physiopathology
  • Ventricular Function, Left/drug effects
Citation (ISO format)
PETAK, Ferenc et al. Prevention of airway hyperresponsiveness induced by left ventricular dysfunction in rats. In: Respiratory research, 2012, vol. 13, n° december, p. 114. doi: 10.1186/1465-9921-13-114
Main files (1)
Article (Published version)
ISSN of the journal1465-9921

Technical informations

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