Enantio- and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins

Tissot, Matthieu; Alexakis, Alexandre

doi:10.1002/chem.201300538

Scientific article

English

Enantio- and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins

Contributors

Tissot, Matthieu; Alexakis, Alexandre

Published in

Chemistry, vol. 19, no. 34, p. 11352-11363

Publication date

2013

Abstract

The copper-catalysed conjugate addition of trialkylaluminium and dialkylzinc reagents to polyconjugated nitroolefins (nitrodiene and nitroenyne derivatives) is reported. A reversed Josiphos ligand L7 allows for the selective 1,4- or 1,6-addition with high enantioselectivities.

Keywords

Asymmetric catalysis
Conjugate addition
Copper
Ligand effects
Phosphine ligands

UNIGE affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

TISSOT, Matthieu, ALEXAKIS, Alexandre. Enantio- and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins. In: Chemistry, 2013, vol. 19, n° 34, p. 11352–11363. doi: 10.1002/chem.201300538

Article (Published version)

Identifiers

PID : unige:29564
DOI : 10.1002/chem.201300538

Journal ISSN

0947-6539

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Creation

02/09/2013 16:53:00

First validation

02/09/2013 16:53:00

Update

14/03/2023 20:23:53

Status update

14/03/2023 20:23:53

Last indexation

30/10/2024 10:08:27

Enantio- and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

Citation (ISO format)

Main files (1)

Identifiers

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation