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Scientific article
Open access
English

Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism

Published inHealth psychology review, vol. 31, no. 2, p. 242-249
Publication date2012
Abstract

Fibromyalgia (FM) has been related to biochemical alterations, central pain sensitization and psychological distress. Among genetic and environmental hypotheses, a role was suggested for catechol-O-methyl-transferase (COMT), a modulator in the metabolism of monoaminergic neurotransmitters.

Keywords
  • Adult
  • Case-Control Studies
  • Catechol O-Methyltransferase/genetics/metabolism/physiology
  • Catechols
  • Depression
  • Female
  • Fibromyalgia/genetics/physiopathology/psychology
  • Genotype
  • Guaiacol
  • Humans
  • Male
  • Middle Aged
  • Pain/genetics
  • Polymorphism, Genetic
  • Stress, Psychological
  • Transferases/genetics
Funding
  • Swiss National Science Foundation - 4053-104645
Citation (ISO format)
DESMEULES, Jules Alexandre et al. Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism. In: Health psychology review, 2012, vol. 31, n° 2, p. 242–249. doi: 10.1037/a0025223
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1743-7199
694views
480downloads

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