Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism

Article Article scientifique Article Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism eng 2012 author Desmeules Jules Alexandre 73542 author Piguet Valérie 64458 author Besson Marie 78338 author Chabert Jocelyne 628070 author Rapiti Aylward Elisabetta 134294 author Rebsamen Michela 83022 author Rossier Michel 22435 author Curtin François 22848 author Dayer Pierre 25460 author Cedraschi Christine 22343 242-249 10.1037/a0025223 21895373 1743-7199 Fibromyalgia (FM) has been related to biochemical alterations, central pain sensitization and psychological distress. Among genetic and environmental hypotheses, a role was suggested for catechol-O-methyl-transferase (COMT), a modulator in the metabolism of monoaminergic neurotransmitters. Adult Case-Control Studies Catechol O-Methyltransferase/genetics/metabolism/physiology Catechols Depression Female Fibromyalgia/genetics/physiopathology/psychology Genotype Guaiacol Humans Male Middle Aged Pain/genetics Polymorphism, Genetic Stress, Psychological Transferases/genetics Dewey 616 Dewey 617 Dewey 618.97 Dewey 613 Swiss National Science Foundation 4053-104645 CH 56 Département de médecine 221 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 215 Registre genevois des tumeurs 22A12 65 Département de réadaptation et gériatrie 22B false 195 Aspects psychosociaux des maladies chroniques 247 1311 Epidémiologie des tumeurs 1017 277 Groupe Bouchardy Magnin Christine (Registre genevois des tumeurs) 532 302 Groupe Desmeules Jules (pharmacologie/toxicologie) 567 Health psychology review 31 2 00de942e-dddf-48cf-91b6-7e5d930301c1 Article (Published version) Public hea-31-2-242.pdf 290584 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale / Registre genevois des tumeurs Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

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Psychological distress in fibromyalgia patients: a role for catechol-O-methyl-transferase Val158met polymorphism	Health psychology review			2012	827	673

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Besson, Marie