Objective: While the broad use of antibiotics has reached its limits with the apparition of bacterial resistance, it became of major importance to regulate antibiotic prescriptions. In this paper, we present KART, a system to facilitate the creation of clinical guidelines in the context of infectious diseases. Methods: This system is composed of three main modules. The first module aims at facilitating the step of systematic reviews with the use of question-answering techniques, in order to create recommendations by querying a question-answering engine. Then, the second module proposes an approach to semi-automatically normalize the different parameters forming clinical recommendations. Finally, the third module aims to automatically formalize and store the generated recommendations into a knowledge repository. Results: The question-answering module is able to answer about two thirds of the queries correctly. The normalization, however, has had very mixed success upon evaluation of the system by infectious diseases specialists. Conclusion: In conclusion, KART is an innovative and promising system to create clinical guidelines; however, preliminary qualitative and quantitative evaluations show the need for further improvements.