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Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice

van Velthoven, Cindy T J
Kavelaars, Annemieke
Zijlstra, Jitske
van Bel, Frank
Heijnen, Cobi J
Published in Annals of neurology. 2012, vol. 71, no. 6, p. 785-96
Abstract A study was undertaken to investigate the effect of neonatal hypoxic-ischemic (HI) brain damage and mesenchymal stem cell (MSC) treatment on the structure and contralesional connectivity of motor function-related cerebral areas.
Keywords Age FactorsAnimalsAnimals, NewbornAnisotropyAntigens, Neoplasm/genetics/metabolismAxons/physiologyBiotin/analogs & derivatives/diagnostic useBrain Ischemia/pathology/surgeryCerebral Cortex/physiopathologyDNA-Binding Proteins/metabolismDextrans/diagnostic useDiffusion Tensor ImagingDisease Models, AnimalFunctional LateralityGreen Fluorescent Proteins/genetics/metabolismLuminescent Proteins/diagnostic useMesenchymal Stem Cell Transplantation/methodsMesenchymal Stromal Cells/physiologyMiceMice, Inbred C57BLMice, TransgenicMyelin Basic Protein/metabolismNeural Pathways/physiologyNuclear Proteins/metabolismPsychomotor Performance/physiologyRecovery of Function/physiologyTime Factors
PMID: 22718545
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Research group L'imagerie cérébrale (184)
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VAN VELTHOVEN, Cindy T J et al. Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice. In: Annals of neurology, 2012, vol. 71, n° 6, p. 785-96. doi: 10.1002/ana.23543 https://archive-ouverte.unige.ch/unige:28595

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Deposited on : 2013-06-17

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