Scientific article
English

Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice

Published inAnnals of neurology, vol. 71, no. 6, p. 785-796
Publication date2012
Abstract

A study was undertaken to investigate the effect of neonatal hypoxic-ischemic (HI) brain damage and mesenchymal stem cell (MSC) treatment on the structure and contralesional connectivity of motor function-related cerebral areas.

Keywords
  • Age Factors
  • Animals
  • Animals, Newborn
  • Anisotropy
  • Antigens, Neoplasm/genetics/metabolism
  • Axons/physiology
  • Biotin/analogs & derivatives/diagnostic use
  • Brain Ischemia/pathology/surgery
  • Cerebral Cortex/physiopathology
  • DNA-Binding Proteins/metabolism
  • Dextrans/diagnostic use
  • Diffusion Tensor Imaging
  • Disease Models, Animal
  • Functional Laterality
  • Green Fluorescent Proteins/genetics/metabolism
  • Luminescent Proteins/diagnostic use
  • Mesenchymal Stem Cell Transplantation/methods
  • Mesenchymal Stromal Cells/physiology
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Myelin Basic Protein/metabolism
  • Neural Pathways/physiology
  • Nuclear Proteins/metabolism
  • Psychomotor Performance/physiology
  • Recovery of Function/physiology
  • Time Factors
Citation (ISO format)
VAN VELTHOVEN, Cindy T J et al. Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice. In: Annals of neurology, 2012, vol. 71, n° 6, p. 785–796. doi: 10.1002/ana.23543
Main files (1)
Article (Published version)
accessLevelPrivate
Identifiers
Journal ISSN0364-5134
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