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Scientific article
English

High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep

ContributorsVan De Looij, Yohan; Lodygensky, Gregory Anton; Dean, Justin; Lazeyras, François; Hagberg, Henrik; Kjellmer, Ingemar; Mallard, Carina; Hüppi, Petra Susan; Sizonenko, Stéphaneorcid
Published inPediatric research, vol. 72, no. 3, p. 285-292
Publication date2012
Abstract

In gyrencephalic species such as sheep, precise anatomical and microstructural characterization of the consequences of fetal inflammation remains scarce. The goal of this study was to characterize changes in white matter (WM) structure using advanced magnetic resonance imaging (MRI) following lipopolysaccharide (LPS) exposure in the preterm-equivalent fetal sheep.

Keywords
  • Animals
  • Brain/anatomy & histology/drug effects
  • Lipopolysaccharides/toxicity
  • Magnetic Resonance Imaging
  • Sheep/embryology
Affiliation entities
Research groups
Citation (ISO format)
VAN DE LOOIJ, Yohan et al. High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep. In: Pediatric research, 2012, vol. 72, n° 3, p. 285–292. doi: 10.1038/pr.2012.72
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Article (Published version)
accessLevelPrivate
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Journal ISSN0031-3998
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