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Title

Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis

Authors
Manrique-Hoyos, Natalia
Grønborg, Mads
Schedensack, Mariann
Kuhlmann, Tanja
Brück, Wolfgang
Urlaub, Henning
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Published in Annals of Neurology. 2012, vol. 71, no. 2, p. 227-44
Abstract To investigate the impact of single or repeated episodes of reversible demyelination on long-term locomotor performance and neuroaxonal integrity, and to analyze the myelin proteome after remyelination and during aging.
Keywords AgingAnimalsAxons/pathology/ultrastructureCuprizone/administration & dosage/toxicityDemyelinating Diseases/chemically induced/pathology/physiopathologyDisease Models, AnimalHumansMiceMice, Inbred C57BLMonoamine Oxidase Inhibitors/administration & dosage/toxicityMotor Skills/drug effects/physiologyMultiple Sclerosis, Chronic Progressive/physiopathologyMyelin Sheath/pathology/physiologyTime Factors
Identifiers
PMID: 22367995
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Structures
Research group La Sclérose en plaques (908)
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MANRIQUE-HOYOS, Natalia et al. Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. In: Annals of Neurology, 2012, vol. 71, n° 2, p. 227-44. https://archive-ouverte.unige.ch/unige:28432

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Deposited on : 2013-06-10

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