TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs

Durual, Stéphane; Rieder, Philippe; Garavaglia, Giovanni; Musardo Filieri, Anna-Rita; Cattani-Lorente, Maria Angeles; Scherrer, Susanne; Wiskott, Anselm

doi:10.1016/j.bone.2012.09.014

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Title		TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs
Authors		Durual, Stéphane Rieder, Philippe Garavaglia, Giovanni Musardo Filieri, Anna-Rita Cattani-Lorente, Maria Angeles Scherrer, Susanne Wiskott, Anselm
Published in		Bone. 2013, vol. 52, no. 1, p. 230-7
Abstract		Titanium nitride oxide (TiNOx) coatings are known for their biocompatibility, hardness and high resistance to corrosion and wear. Further, they can be applied by plasma vapor deposition onto a wide variety of metallic, mineral, or organic substrates. In cell cultures, TiNOx coatings applied onto SLA (sandblasted, large grit, acid etched)-roughened titanium surfaces increased human primary osteoblast proliferation by 1.5 times in the first 2 weeks after seeding, while maintaining a high degree of cell differentiation. Therefore, the objectives of the present study were (i) to determine whether these findings would translate into the enhanced osseointegration of TiNOx-coated implants in vivo and (ii) to compare the osseointegration of Ti-SLA (titanium-SLA) and CoCr-SLA (cobalt-chromium-SLA) implants coated with TiNOx.
Keywords		Animals — Cell Differentiation — Chromium Alloys — Dental Implants — Osseointegration — Swine — Swine, Miniature — Titanium
Identifiers		DOI: 10.1016/j.bone.2012.09.014 PMID: 23000509
Full text		Article (Published version) (2.5 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine dentaire / Département de médecine dentaire préventive et de premier recours / Division de cariologie et d'endodontie Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division de prothèse fixe et biomatériaux
Research group		Groupe Susanne Scherrer : Unité des biomatériaux (315)
Citation (ISO format)		DURUAL, Stéphane et al. TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs. In: Bone, 2013, vol. 52, n° 1, p. 230-7. doi: 10.1016/j.bone.2012.09.014 https://archive-ouverte.unige.ch/unige:27974