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TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs |
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Published in | Bone. 2013, vol. 52, no. 1, p. 230-7 | |
Abstract | Titanium nitride oxide (TiNOx) coatings are known for their biocompatibility, hardness and high resistance to corrosion and wear. Further, they can be applied by plasma vapor deposition onto a wide variety of metallic, mineral, or organic substrates. In cell cultures, TiNOx coatings applied onto SLA (sandblasted, large grit, acid etched)-roughened titanium surfaces increased human primary osteoblast proliferation by 1.5 times in the first 2 weeks after seeding, while maintaining a high degree of cell differentiation. Therefore, the objectives of the present study were (i) to determine whether these findings would translate into the enhanced osseointegration of TiNOx-coated implants in vivo and (ii) to compare the osseointegration of Ti-SLA (titanium-SLA) and CoCr-SLA (cobalt-chromium-SLA) implants coated with TiNOx. | |
Keywords | Animals — Cell Differentiation — Chromium Alloys — Dental Implants — Osseointegration — Swine — Swine, Miniature — Titanium | |
Identifiers | PMID: 23000509 | |
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Research group | Groupe Susanne Scherrer : Unité des biomatériaux (315) | |
Citation (ISO format) | DURUAL, Stéphane et al. TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs. In: Bone, 2013, vol. 52, n° 1, p. 230-7. doi: 10.1016/j.bone.2012.09.014 https://archive-ouverte.unige.ch/unige:27974 |