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Title

TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs

Authors
Musardo Filieri, Anna-Rita
Published in Bone. 2013, vol. 52, no. 1, p. 230-7
Abstract Titanium nitride oxide (TiNOx) coatings are known for their biocompatibility, hardness and high resistance to corrosion and wear. Further, they can be applied by plasma vapor deposition onto a wide variety of metallic, mineral, or organic substrates. In cell cultures, TiNOx coatings applied onto SLA (sandblasted, large grit, acid etched)-roughened titanium surfaces increased human primary osteoblast proliferation by 1.5 times in the first 2 weeks after seeding, while maintaining a high degree of cell differentiation. Therefore, the objectives of the present study were (i) to determine whether these findings would translate into the enhanced osseointegration of TiNOx-coated implants in vivo and (ii) to compare the osseointegration of Ti-SLA (titanium-SLA) and CoCr-SLA (cobalt-chromium-SLA) implants coated with TiNOx.
Keywords AnimalsCell DifferentiationChromium AlloysDental ImplantsOsseointegrationSwineSwine, MiniatureTitanium
Identifiers
PMID: 23000509
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Research group Groupe Susanne Scherrer : Unité des biomatériaux (315)
Citation
(ISO format)
DURUAL, Stéphane et al. TiNOx coatings on roughened titanium and CoCr alloy accelerate early osseointegration of dental implants in minipigs. In: Bone, 2013, vol. 52, n° 1, p. 230-7. doi: 10.1016/j.bone.2012.09.014 https://archive-ouverte.unige.ch/unige:27974

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Deposited on : 2013-05-24

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